CCCZ Research Area – Imaging, Technology Development and Digitalization

Focus topics

• Innovative MRI sequences and targeted PET tracers
• Quantitative image analysis and radiomics
• High-throughput diagnostics
• Bioinformatincs, especially machine learning, artificial intelligence and deep learning
• Multi-systems decision-making algorithms for treatment planning and response assessment
• Image-guided treatment
• Computer-aided drug design
• Virus vectors in anti-cancer treatments
• Protein engineering to develop new protein therapeutics
• Radioactively labeled molecules for innovative, targeted tumor therapies

Specific Aims

• Develop and apply methods for computer-aided drug design, i.e. epigenetics targets (bromodomains) and RNA-binding proteins (m6A readers)
• Using virus vectors for anti-cancer treatments
• Establish radiomics biomarkers as a standard component in personalized health outcome modelling
• Use protein engineering to develop new protein therapeutics
• Develop radioactive drugs for non-invasive diagnosis and therapy of metastatic cancerous lesions

Research groups

• Nikola Biller-Andorno, Prof. Dr. med. Dr. phil., Biller-Andorno Group 
• Amedeo Caflisch, Prof. Dr., Calfisch Group
• Daniel Eberli, Prof. Dr. Dr. med., Eberli Group
• Thomas Frauenfelder, Prof. Dr. med., Radiology Research Group
• Urs Greber, Prof. Dr., Greber Group
• Matthias Guckenberger, Prof. Dr. med., Radiomics Research Group
• Jürg Hodler, Prof. Dr. med., Diagnostic anc Interventional Radiology
• Michael Krauthammer, Prof. Dr., Clinical Data Science and Translational Bioinformatics Group
• Andreas Plückthun, Prof. Dr., Protein engineering
• Luca Regli, Prof. Dr. med., Neurosurgery
• Roger Schibli, Prof. Dr., Radiopharmaceutical Sciences
• Berend Snijder, Prof. Dr., Snijder Lab