The diagnosis of suspected cardiac amyloidosis is often not easy, and senile ATTR amyloidosis in particular is therefore likely to be underdiagnosed.
However, ATTR amyloidosis, in particular, can be easily diagnosed using a simple skeletal scintigraphy. Although it is still unclear by which mechanism the bone-specific tracers (e.g. DPD) attach to the amyloid in the heart, the skeletal scintigraphy shows a positive predictive value of 100% here (with AL amloidosis excluded at the same time, i.e. negative serum and urine Electrophoresis; Gillmore et al. Circulation. 2016 Jun 14; 133 (24): 2404-12) for the diagnosis of ATTR amyloidosis (Figure 5). There are no special preparations required for this diagnotic procedure.
Director of the Department of Nuclear Medicine, Department of Nuclear Medicine
Director USZ Airport - The Circle, Department of Nuclear Medicine
Nuclear Medicine Physician, Department of Nuclear Medicine
Cardiologist, Department of Nuclear Medicine
Internist, Department of Nuclear Medicine
Senior Attending Physician, Department of Nuclear Medicine
Deputy Clinic Director , Department of Nuclear Medicine
Nuclear Medicine Physician, Department of Nuclear Medicine
Cardiologist, Department of Nuclear Medicine
Attending Physician, Department of Nuclear Medicine
Senior Attending Physician, Department of Nuclear Medicine
Cardiologist, Department of Nuclear Medicine
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