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Tyrosine PET (Neurooncology)

Tyrosine is a natural amino acid and an endogenous substance. 18F-ethyltyrosine (FET) is a tracer that, like amino acids, is taken up by brain-derived tumors and brain metastasis, but hardly by normal brain tissue. Therefore, the tracer is ideally suited for the evaluation of brain-derived tumors, metastases and for recurrence after therapy. To a certain extent therapy-induced changes in the brain can also be distinguished from tumor recurrences with Tyrosine PET.

MRI Aufnahme eines Gehirns mit Astrozytom
High tracer uptake (arrows) at the resection margin in recurrent astrocytoma WHO grade III.

Indications

The following indications are reimbursed by the health insurance:

  • Evaluation of brain tumors (e.g., to find the best biopsy site).
  • Re-evaluation of malignant brain tumors
Details see PDF, page 105ff

Responsible doctors

Martin Hüllner, PD Dr. med.

Senior Attending Physician, Department of Nuclear Medicine
Deputy Clinic Director, Department of Nuclear Medicine
Nuclear Medicine Physician, Department of Nuclear Medicine
Radiologist, Department of Nuclear Medicine
Diagnostic Neuroradiologist, Department of Nuclear Medicine

Specialties: Oncological, neurological and musculoskeletal imaging
Tel. +41 44 255 25 80

Lars Husmann, Prof. Dr. med.

Attending Physician, Department of Nuclear Medicine
Nuclear Medicine Physician, Department of Nuclear Medicine
Radiologist, Department of Nuclear Medicine

Specialties: PET/CT Imaging
Tel. +41 43 253 87 99

David Kenkel, PD Dr. med.

Attending Physician, Department of Nuclear Medicine
Radiologist, Department of Nuclear Medicine

Specialties: Oncological imaging (PET, SPECT, CT, MRI)

Cäcilia Mader, Dr. med.

Senior Attending Physician, Department of Nuclear Medicine
Nuclear Medicine Physician, Department of Nuclear Medicine
Radiologist, Department of Nuclear Medicine
Neuroradiologist, Department of Nuclear Medicine

Specialties: Oncological, neurological and musculoskeletal hybrid imaging
Tel. +41 43 253 88 02

Alexander Maurer, Dr. med.

Attending Physician, Department of Nuclear Medicine
Nuclear Medicine Physician, Department of Nuclear Medicine
Radiologist, Department of Nuclear Medicine

Specialties: Oncologic imaging, Hybrid imaging of prostate cancer
Tel. +41 43 253 88 09

Michael Messerli, PD Dr. med.

Attending Physician, Department of Nuclear Medicine
Nuclear Medicine Physician, Department of Nuclear Medicine
Radiologist, Department of Nuclear Medicine

Specialties: Hybrid imaging of oncological diseases (PET, SPECT, CT, MRI)
Tel. +41 43 253 88 03

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