Bacterial interspecies interactions in the human host as a source for microbiota-targeted therapies
Projects
Bacterial interspecies interactions in the upper respiratory tract – microbiota engineering for prevention of invasive disease (Promedica Foundation, Walter und Gertrud Siegenthaler Stiftung).
The bacterial microbiota in burn patients – understanding microbial evolution under antibiotic selection pressure for future therapeutic and preventive approaches (Béatrice-Ederer-Weber Foundation. Collaboration with Philipp Bühler).
MRSA/MSSA eradication with commensals. (Gebert Rüf Foundation, Microbials Grant. Collaboration with Lucio Isa and Markus Hilty).
KFSP – BacVivo – Precision medicine for bacterial infections. Clinical Research Priority Programm (CRPP) University of Zürich
SARS-CoV-2-Induced Immune Alterations and their Role in Post-COVID Syndrome. (The Loop Zurich / Helmut Horten Stiftung, lead Roland Martin)).
Protective and Pathogenic T Cell Immunity During SARS-CoV-2 Infection. (SNF, Lead Roland Martin).
Members
Pascal M. Frey, M.D., M.Sc., PostDoc, Epidemiologist Project: Quantitative Fitness Analysis (QFA), Epidemiology of Infectious Diseases
Thomas C. Scheier, M.D., ID Fellow Project: VRE detection, novel typing methods Collaboration: PD Alban Ramette, University of Bern
Jeruscha Baum, M.Sc., PhD Student Project: MRSA/MSSA eradications with commensals Funding: Gebert-Rüf-Foundation Collaboration: Prof. Lucio Isa, ETHZ, PD Markus Hilty, University of Bern
Judith Bergada Pijuan, M.Sc., PhD-Student Project: Molecular mechanisms mediating the inhibition of human upper respiratory tract pathobionts by the commensals Dolosigranulum pigrum and Corynebacterium pseudodiphtheriticum Funding: Promedica Foundation Collaboration: Prof. Mattia Zampieri, ETHZ
Giorgio Beringer, M.D.-Ph.D., Student Project: S. argenteus virulence and population diversity
Joint supervision with Prof. A. Zinkernagel
Chun-Chi Chang, M.Sc. PhD-Student Project: Commensals in human upper respiratory tract and host innate immunity: Modulating functional capacity of innate immune response by nasal commensals against pathobionts
Joint supervision with Prof. A. Zinkernagel and Dr. S. Mairpady Shambat Project: The bacterial microbiota in burn patients – understanding microbial evolution under antibiotic selection pressure for future therapeutic and preventive approaches Funding: Béatrice-Ederer-Weber Foundation Collaboration: Dr. Philipp Bühler, USZ, Dr. Srikanth Mairpady Shambat, USZ
Funding
Promedica Foundation, Béatrice-Ederer-Weber Foundation, Walter und Gertrud Siegenthaler Foundation, Swiss National Science Foundation (SNF), The Loop Zurich (Helmut Horten Foundation), KFSP – BacVivo – Precision medicine for bacterial infections.Clinical Research Priority Programm (CRPP) University of Zürich.
Previous Funding: Swiss National Science Foundation (SNF), Swiss Foundation for Grants in Biology and Medicine (SFGBM), Novartis Foundation for Medical-Biological Research.
Collaborations
Annelies Zinkernagel, Dr. Srikanth Mairpady Shambat, PD Dr. Barbara Hasse, Department of Infectious Diseases and Hospital Epidemiology, USZ
Nicolas Müller, Department of Infectious Diseases and Hospital Epidemiology, USZ
Lucio Isa, ETHZ
Roland Marin, Dr. Ilijas Jelcic, MIMS, USZ
Roger Koyos, Dr. Burcu Tepekule, Department of Infectious Diseases and Hospital Epidemiology, USZ
Philipp Bühler and Prof. Reto Schüpbach, Institute for Intensive Care Medicine, University Hospital Zürich, Switzerland
PD Dr. Markus Hilty and PD Dr. Alban Ramette, Institute for Infectious Diseases, University of Bern, Switzerland
Katherine P. Lemon, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA
Melinda M. Pettigrew, Yale School of Public Health, New Haven, CT, USA
Lukas Flatz, University of Tübingen
Mattia Zampieri, ETHZ
Sven Hobbie, Institute for Medical Microbiology, UZH
David Holzmann, PD Dr. Michael Soyka, Department of ENT, USZ
Prof. Emma Slack, ETHZ
Publications
You can find all current publications of the research group on the National Library of Medicine.