Research Group PD Dr. med. Daniel Hofmänner
Our group investigates the role of lipids in sepsis, therapeutic drug monitoring in critically ill patients, and strategies to improve ICU patient safety. Our research explores how inflammation affects blood lipid profiles and their potential as treatment targets. We also evaluate drug monitoring effectiveness in patients on extracorporeal support and use eye tracking to assess clinical awareness and reduce human error.
Projects
- Assessment of the impact of lipid alterations on outcomes in patients with cardiogenic shock
- Assessment of the impact of lipid alterations on infectious complications in patients with cardiogenic shock
- Influence of extracorporeal membrane oxygenation on serum levels of antimicrobial substances
- Influence of extracorporeal membrane oxygenation on drug dosing of antimicrobial substances
- Analysis of visual behaviour of critical care professionals
- Assessment of situational awareness during high-risk interventions
Publications
- Hofmaenner DA, Kleyman A, Press A, Bauer M, Singer M. The Many Roles of Cholesterol in Sepsis: A Review. Am J Respir Crit Care Med. 2022 Feb 15;205(4):388-396.
- Labilloy G, Tanaka S, Black LP, Augustin B, Hopson C, Bethencourt J, Wu D, Sulaiman D, Bertrand A, Salomão R, Graim K, Datta S, Reddy S, Guirgis FW, Hofmaenner DA. Identifying a Sepsis Subphenotype Characterized by Dysregulated Lipoprotein Metabolism Using a Simplified Clinical Data Algorithm. Shock. 2025 Apr 23.
- Camen G, Wendel-Garcia PD, Erlebach R, Müller M, John C, Buhlmann A, Andermatt R, Schuepbach RA, David S, Hofmaenner DA. Teicoplanin pharmacokinetics in critically ill patients on extracorporeal organ support: a retrospective analysis. Intensive Care Med Exp. 2025 Feb 21;13(1):22.
- Lohmeyer Q, Schiess C, Wendel Garcia PD, Petry H, Strauch E, Dietsche A, Schuepbach RA, Buehler PK, Hofmaenner DA. Effects of tall man lettering on the visual behaviour of critical care nurses while identifying syringe drug labels: a randomised in situ simulation. BMJ Qual Saf. 2023 Jan;32(1):26-33
- Valek R, Wendel-Garcia PD, Schuepbach RA, Buehler PK, Hofmaenner DA. Eye-tracking to observe compliance with hand hygiene in the intensive care unit: a randomized feasibility study. J Hosp Infect. 2023 Jan;131:148-155.
- Nicole Schweizer (Doktorandin)
- Lisa Lei Peter (Doktorandin)
- Anna Schwesinger (Doktorandin)
- Alessandro Longhi (Doktorand)