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“Quadruplets are (also) a logistical challenge”

Quadruplets were born at the USZ at the beginning of March. Despite thousands of births, this is also a rare occurrence at the USZ. This is also the case for Beate Grass, Head Physician at the Neonatology Clinic, and Nina Kimmich, Head Physician at the Obstetrics Clinic.

Ms. Grass, Ms. Kimmich, how often are children in a “four-pack”?

There are already few triplet births; 19 triplet births were recorded in Switzerland in 2020 and 2022, and eleven in 2021. Quadruplets or even quintuplets are even rarer. There was only one such multiple birth in Switzerland in 2020, and none at all in 2021 and 2022.

How frequent are quadruplet births at the USZ?

We had one quadruplet birth each at the USZ in 1995, 2005, 2015 and now 2024.

Why are quadruplet births so rare?

Most quadruplet pregnancies end on their own in the early stages or in the first half of the pregnancy because one or more children are not completely healthy or there is an early rupture of the membranes, bleeding with contractions or other complications.

What is the challenge of multiple births for neonatology?

Quadruplets are always born prematurely. They need appropriate neonatal support over a period of weeks to months. However, the health problems and medical measures for quadruplets do not differ from those of individual premature babies. Quadruplets are a logistical challenge for neonatology teams and appropriate resource planning is required for the birth, as all four children have to receive intensive medical care at the same time. After initial care in the delivery room, the children are taken to the neonatology department. Admission capacity must also be created here at short notice, e.g. by transferring children so that the multiples can receive intensive medical care there.

What determines the time of birth?

A caesarean section is always performed for the delivery of quadruplets. However, this does not mean that the timing can be planned well in advance. The decisive factor is ultimately the medical situation. In most cases, mothers go into labor too early or their water breaks much too early, which in turn can trigger contractions, but can also lead to an infection. Other reasons may be growth retardation of one or more children due to a reduced supply to the placenta or impaired blood circulation. As the pregnancy progresses, reasons such as maternal exhaustion, breathing difficulties and sleep disturbances due to the large abdominal girth come to the fore in the decision to give birth.

How do you prepare for the birth in the participating clinics?

The care and birth of quadruplets is a major organizational and personnel challenge, especially when it comes to cooperation and coordination between all the specialists and disciplines involved. As mentioned, quadruplets are often born unplanned and often at the weekend or at night, so a good plan is needed in advance, just in case. The most experienced doctors are called in for the birth of quadruplets. When the birth is due, they also come to the USZ from home outside of their working hours to provide the best possible care for the mother and children.

Who is there for such a demanding and rare birth?

A great team! The neonatology department alone has two to three doctors and one nurse available for each child. That’s already 12 to 16 people. In addition, there are three obstetricians, three midwives, two anesthetists, one anesthesia nurse and two surgical nurses.

After two months in neonatology, the quadruplets were allowed to go home. This is a big step for the parents. What advice do you give parents? Do you follow the children’s development?

Caring for premature quadruplets at home over a long period of time is very demanding. Leaving hospital requires good planning and the establishment of a support network in advance. We will closely follow the development of the quadruplets throughout their childhood. However, we do this for all premature and extremely premature babies in Switzerland.

Responsible professionals

Beate Grass, PD Dr. med.

Senior Physician, Department of Neonatology

Tel. +41 44 255 11 11
Specialties: Intensive care medicine for premature and newborn babies, Neonatal transport medicine, Neonatal simulation

Nina Kimmich, PD Dr. med.

Senior Physician, Department of Obstetrics

Tel. +41 44 255 11 11
Specialties: Specialist in fetomaternal medicine, FMH, Invasive and non-invasive prenatal diagnostics, Birth injuries/postpartum pelvic floor diagnostics