68Ga-DOTATATE PET/CT is the most sensitive exam to detect well-differentiated neuroendocrine tumors. Well-differentiated neuroendocrine tumors do not have an increased sugar metabolism and therefore cannot be detected with 18F-FDG-PET/CT. On the other hand, they have a receptor on the cell surface (SSTR - somatostatin receptor) to which 68Ga-DOTATATE binds and can thus make the tumor visible. This procedure has replaced octreotide scintigraphy in our clinic, as smaller lesions are better detected and can be precisely localized thanks to the combination of PET and CT.
On the axial fused images, a focal DOTATATE multiple accumulation can be localized in the pancreas (red arrow), which corresponds to a small neuroendocrine tumor that could not be delineated by CT. There is also a lymph node metastasis dorsal to the pancreas (yellow arrow).
The following indication is covered by health insurance:
In the brain, 68Ga-DOTATATE-PET/CT is suitable for clarifying meningiomas and meningioma recurrences, e.g. prior to radiation planning.
High tracer uptake in the meningioma
The following indication is covered by health insurance:
Senior Physician, Vice Director of Department, Department of Nuclear Medicine
Attending Physician, Department of Nuclear Medicine
Senior Attending Physician, Department of Nuclear Medicine
Senior Attending Physician, Department of Nuclear Medicine
Senior Attending Physician, Department of Nuclear Medicine
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