Puncture (FNP) - Outpatient clinic
Fine needle aspiration (FNP) is a diagnostic procedure that can often clarify the nature of an unclear swelling, lump or organ enlargement quickly and easily. Fine needle aspiration can be performed by doctors from various disciplines.
Fine needle aspiration in the cytopathology outpatient puncture center USZ
The cytopathologists at our institute carry out FNPs of superficial lesions in the department’s own fine needle aspiration ambulatory, which also guarantees the high quality of the sample. The procedure is comparable to injecting a syringe when taking a blood sample. A very thin needle (usually 0.55 mm in diameter) is used to extract cells from the pathological change, which are then examined under a microscope for any changes.
In our outpatient clinic, FNPs are carried out primarily for changes in the following organs:
- Thyroid gland
- Salivary gland
- Lymph nodes
- Soft tissue and skin
- Breast and breast cysts
Cytopathology General/FNP
Site plan outpatient clinic
External fine needle aspiration
The processing and assessment is exactly the same for FNP samples that are carried out by doctors from other clinics – USZ internal or external – (e.g. radiology, ear, nose and throat clinic, gastroenterology, pneumology, dermatology, gynecology, oncology, etc.) and sent to us.
Cancer screening PAP smear
The assessment of cell changes in PAP smears in combination with HPV testing is essential for the prevention and detection of precancerous stages of cervical cancer.
The PAP smear is taken from the surface of the cervix by the gynecologist during the gynecological examination and sent to our cytology institute for diagnosis. The cytopathologists prepare a report on the possible detection of precancerous cells. Depending on the result, HPV typing can be carried out. Depending on the findings, the gynecologist will arrange further treatment or check-ups based on the cytological analysis of the pap smear, any HPV detection and taking into account the patient’s medical history.
HPV typing
HPV diagnostics is an established molecular detection method for cytological samples. Depending on the test procedure, an infection with human papillomavirus (HPV) can be differentiated as high-risk or low-risk.
Using a modern procedure, we can not only quickly and reliably detect 28 relevant HPV types, but also identify them individually (19 high-risk and 9 low-risk). This can be taken into account, for example, when assessing mixed infections and the question of a persistent infection. Thanks to our direct connection to the molecular pathology laboratory at the University Hospital, it is also possible to detect numerous other rare HPV subtypes.
HPV diagnostics is possible with thin-layer cytology samples directly from the existing sample container, so that the patient does not have to repeat the collection for HPV diagnostics.
Molecular diagnostics
Cytological sample material is generally very well suited for the most modern molecular pathological examinations. Thanks to our close collaboration with the molecular pathology department at the University Hospital, we can directly implement the latest scientific developments and offer innovative, new diagnostic methods: For example, unclear salivary gland lesions or soft tissue tumors can be further classified using so-called NGS examinations.
In addition, extended pathogen diagnostics (e.g. in the case of unclear lymphadenopathy) or immunohistochemical characterization of unclear focal findings or questionable metastases can be carried out directly on cytological samples.
A prerequisite for this diagnosis is appropriately preserved sample material – we therefore recommend a puncture in our outpatient clinic for specific questions about superficial lesions or focal findings in order to enable technically optimal, direct processing.
