PMOS (formerly PCOS) – Zurich Center

PMOS – What Is It?

Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a condition with a wide range of clinical presentations and is the most common endocrine disorder in young women. Some sufferers experience irregular (oligomenorrhea) or absent bleeding (amenorrhea). In rare cases, menstrual cycles are shortened (polymenorrhea). Others suffer from skin problems or increased body hair, possibly due to increased male hormones in the blood (hyperandrogenemia). Often, but not always, the ovaries contain an increased number of small follicles. However, these are not true ovarian cysts, but rather small follicles whose development has stalled. The former term “Polycystic Ovary Syndrome (PCOS)” was therefore misleading and has been replaced by the new term “Polyendocrine Metabolic Ovary Syndrome (PMOS).” This approach better reflects the current understanding of the disease as a disorder affecting the hormonal, metabolic, and ovarian systems.

Why is a PMOS diagnosis important?

PMOS can lead to long-term health consequences such as cardiovascular disease, obesity, diabetes mellitus, mental health conditions such as depression, or even uterine cancer (endometrial carcinoma). In addition, the many follicles can prevent regular ovulation and thus lead to reduced fertility. Cosmetic issues (excessive body hair, acne) can also affect your quality of life

Treatment at the PMOS Center

Our PMOS Center offers modern, personalized treatments to alleviate symptoms and improve quality of life:

• Drug therapies: Regulation of the hormone balance or treatment of cycle disorders (e.g. birth control pills, antiandrogens, luteal hormones or other hormone preparations without contraceptive protection). Medication for weight reduction. Topical medication for hair loss.
• Fertility treatment: stimulation of ovulation or support through IVF if required.
• Dermatological therapies: Laser treatments for increased body hair. Antibiotic treatments for acne.

Why Choose the PMOS Center in Zurich

• Interdisciplinary care: Experts from reproductive endocrinology, endocrinology, dermatology, nutritional medicine and psychology work closely together.
• State-of-the-art diagnostics and therapy: access to the latest scientific findings and technologies for precise diagnosis and effective treatment.
• Individual, patient-centered treatment: A treatment plan tailored to the needs of each patient for the best possible results.
• Research and Innovation: As a university-affiliated center, the USZ actively conducts research to gain new insights into PMOS and continuously improves diagnostic and treatment options.

Our PMOS Experts

Based on the latest scientific findings, experts from various disciplines offer a wide range of counseling and therapy services at PMOS. The clinics for Reproductive Endocrinology, Endocrinology, Diabetology, Clinical Nutrition and Dermatology work closely together. Depending on the individual situation, we offer psychological support and other therapies (e.g. exercise therapy) in and outside the USZ.