Master Student position: System biology and epigenetic changes in rheumatic disease

Short description

There is an unmet need for novel therapies, biomarkers and humanized models for rheumatic diseases. Our laboratory focuses on the analysis of molecular pathways in inflammation, cartilage destruction and multi organ fibrosis. We investigate epigenetic mechanisms such as post-transitional histone modifications, DNA methylation and non-coding RNAs, as well as signaling pathways in primary cells (fibroblasts, monocytes) derived from patients’ biopsies and peripheral blood and 3D-cell cultures. Master students can select between different topics within the field of rheumatology including rheumatoid arthritis, systemic sclerosis and vertebral bone marrow lesions (modic changes).

Keywords

Epigenetics, inflammation, fibrosis, RNA Sequencing, 3D cultures

Conditions

We are looking for enthusiastic master students. Basic knowledge of techniques in molecular biology is of advantage.