Professional article

Multiple births: challenges and opportunities

Multiple pregnancies pose particular challenges, from malformations to premature births with the risk of cerebral hemorrhage. It is essential that pregnant women are cared for in an appropriate competence center.

Feto-fetal transfusion syndrome is a significant complication of multiple births. This can lead to life-threatening situations, as both children depend on the same care. “It is crucial to consider not only the number of children, but also whether each child has its own supply. If they share a placenta, this is associated with higher risks,” says Nicole Ochsenbein, Director of the Department of Obstetrics at the USZ. Early diagnosis and appropriate care for pregnant women are therefore crucial for the outcome of these children.

Second opinion and interdisciplinary collaboration

Feto-fetal transfusion syndrome occurs in 10 to 15 percent of cases. One child gives the other child too much blood in the net flow, which can put such a strain on the heart that it can lead to water retention, for example. In the worst case scenario, the child dies and since both children are dependent on the same care, the other child may also die. Or a child survives severely disabled because the brain has received too little oxygen. This is the case for 20 to 30 percent. “In these ethically highly complex cases, it makes sense to look after the patient together. Referring physicians often send their patients to us for a second opinion,” says Nicole Ochsenbein.

In cases of multiple pregnancies, pregnant women should be cared for in centers that have the necessary expertise. For certain diagnoses, the recommendation is clear in this regard, including in the case of pregnancies with triplets or higher-order multiples. A second opinion can be helpful in making the best possible decisions. Interdisciplinary teams, such as those at the USZ from all relevant fields such as obstetrics, neonatology and other specialists, are crucial to ensure the right care.

Competence center with highly specialized medicine

If there is a complication, such as the aforementioned feto-fetal transfusion syndrome, the specialists at the USZ can take action and offer appropriate treatment. “Laser treatment is available for this complication, in which the vascular connections in the shared placenta are selectively obliterated. This therapy requires precision and specialist knowledge,” confirms Nicole Ochsenbein.

Thanks to the fetal-maternal boards at the USZ, obstetrics and neonatology specialists regularly exchange information with specialists from the children’s hospital. “This also gives us important feedback on the outcome of the children. This extensive know-how is invaluable when advising parents and creates trust among patients,” says Nicole Ochsenbein.

Aftercare and breastfeeding

Premature births are the most common complication of multiple pregnancies. The probability of a premature birth increases with the number of children. Even in uncomplicated pregnancies, multiples are often born prematurely. The obstetrics department at the USZ therefore employs a large number of feto-maternal specialists. A senior physician with the appropriate qualifications is always available around the clock.

Follow-up care is usually provided by the referring doctors. Breastfeeding is particularly important with multiples and often requires special support. Breastfeeding consultants are available at the USZ to instruct mothers on breastfeeding twins.

Nicole Ochsenbein is convinced that the management of multiple pregnancies requires close collaboration between referring physicians, the interdisciplinary teams at the USZ and the patients themselves: “Early detection of complications and appropriate treatment are crucial to ensure the health of mother and child. Holistic care, from pregnancy to aftercare, is of great importance to us in order to achieve the best possible outcome for multiple birth families.”

Nicole Ochsenbein-Kölble, Prof. Dr. med.

Director of Department, Department of Obstetrics

Tel. +41 44 255 11 11
Specialties: Specialist in fetomaternal medicine, FMH, Specialist title in surgical gynecology and obstetrics, FMH, Multiple births, fetal surgery, laser therapy

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