Wir, das CTC unterstützen Forschende bei der Durchführung klinischer Studien – kompetent, praxisnah und verlässlich. Gleichzeitig engagieren wir uns in eigenen Forschungsprojekten und teilen unsere Erkenntnisse laufend mit der Fachwelt.
2026
Bernasconi, L., Kapaklikaya, Z., Grossmann, R. (2026): Between promise and practice: Exploring AI’s role in research participant communication. In: Sage Journals, Research Ethics.https://doi.org/10.1177/17470161261419861
2025
Coralie Dirler, Vinzenz Boos, Dirk Bassler, Stephan Benke-Bruderer, Ulrike Held, Christoph M. Rüegger Tobias Muehlbacher. Pain Assessment During Less Invasive Surfactant Administration Using Skin Conductance: A Prospective Cohort Study. In: Pedriatric Research: https://doi.org/10.1038/s41390-025-04703-9
Bley, M., Mathez, L., Menz, S., Stephan, I., Regitz‑Zagrosek, V., Lerchenmueller, M.J., Lerchenmüller, C. (2025): Consideration of sex/gender aspects in cardiovascular clinical trials. In: Clinical Research in Cardiology Nov 26. https://doi.org/10.1007/s00392-025-02793-3
Bernasconi, L., Avakyan, G., Hovaguimian, F., Grossmann, R. (2025) : Natural Language Processing in Clinical Research Recruitment: A Scoping Review Enriched with Stakeholder Insights. In: Ethics & Human Research 47(5): 13-23. http://dx.doi.org/10.1002/eahr.60014
Griessbach, A., Chiaborelli, M., Ehrlich, K., Grossmann, R., De Medina Redondo, M., Fayet, A., Maier, R., Trelle, S., Gayet-Ageron, A., Ceschi, A., Speich, B., Briel, M.; MAking Randomized Trials Affordable (MARTA) Group (2025): Clinical trial budgeting approaches in Switzerland – a meta-research study. In: Trials, 26:158. https://doi.org/10.1186/s13063-025-08855-1
Bernasconi, L., Grossmann, R. (2025): Navigating the future of clinical trial management – insights on the transformative role of AI. In: Research Ethics (OnlineFirst, Jan 3, 2025). https://doi.org/10.1177/17470161241309347
Pausch A. M.,Ghafoor S., Notter R., Benke-Bruderer St., von Felten St., Rupp N. J., Eberli D., Hötker A. M.
MRI-based risk stratification for clinically significant prostate cancer detection at biopsy: The value of zonal-specific PSA density and PSHS In: European Journal of Radiology, Volume 184, March 2025, 111982 https://doi.org/10.1016/j.ejrad.2025.111982
Roos J., Bauer A., Griessbach A., Grossmann R; Socio-demographic and clinical factors affecting General Consent status and choice: insights from a cross-sectional study of University Hospital Zurich patients. In: Swiss Med Wkly. 2025;155:3685. https://doi.org/10.57187/s.3685
2024
Petersen, J.J., Hemberg, L., Thabane, L., Hopewell, S., Chan, A.-W., Hróbjartsson, A., Mathiesen, O., Sergeant, M., Kandasamy, S., Siegfried, N., Williamson, P.R., Fox, L., Barkholt Kamp, C., Hoffmann, J.-M., Brorson, S., Bentzer, P., Jakobsen, J.C. (2024): Integrating environmental outcomes in randomised clinical trials: a call to action. In: The Lancet, 405(10477), 446–448. https://doi.org/10.1016/S0140-6736(24)02666-7
Eberle, D., Bauer, A., Landgraf, C., Roos, J., Grossmann, R. (2024): Patient and public involvement in academic clinical research in Switzerland – a mixed methods study. In: Swiss Medical Weekly, 154:3563. https://doi.org/10.57187/s.3563
Hoffmann, J.-M., Bauer, A., Grossmann, R. (2024): Academic vs. industry-sponsored trials: A global survey on differences, similarities, and future improvements. In: Journal of Global Health, 14:04204 (November 22, 2024). https://doi.org/10.7189/jogh.14.04204
Ormond, K.E., Bavamian, S., Becherer, C., Currat, C., Joerger, F., Geiger, T.R., Hiendlmeyer, E., Maurer, J., Staub, T., Vayena, E. (2024): What are the bottlenecks to health data sharing in Switzerland? An interview study. In: Swiss Medical Weekly, 154(1):3538. https://doi.org/10.57187/s.3538
2023
Hoffmann, J.-M., Bauer, A., Grossmann, R. (2023): The carbon footprint of clinical trials: a global survey on the status quo and current regulatory guidance. In: BMJ Global Health. https://doi.org/10.1136/bmjgh-2023-012754
Hoffmann, J.-M., Blümle, A., Grossmann, R., Yau, H., Lang, B., Bradbury, C. (2023): Toward a global harmonization of service infrastructure in academic clinical trial units: an international survey. In: Frontiers in Medicine (Lausanne), 10:1252352. https://doi.org/10.3389/fmed.2023.1252352
2022
Hoffmann, J.-M., Grossmann, R., Widmann, A. (2022): Academic clinical trials: Publication of study results on an international registry—We can do better! In: Frontiers in Medicine. https://doi.org/10.3389/fmed.2022.1069933
Griessbach, A., Bauer, A., Jörger Lebet, F., Grossmann, R. (2022): The concept of General Consent in Switzerland and the implementation at the University Hospital Zurich, a cross-sectional study. In: Swiss Medical Weekly, 152:w30159. https://doi.org/10.4414/SMW.2022.w30159
Bauer, A., Eskat, A., Ntekim, A., Wong, C., Eberle, D., Hedayati, E., Tay, F., Yau, H., Stockley, L., de Medina Redondo, M., Şen, S., Egert-Schwender, S., Üresin, Y., Grossmann, R. (2022): How COVID-19 changed clinical research strategies: a global survey. In: Journal of International Medical Research, 50(4), 3000605221093179. https://doi.org/10.1177/03000605221093179
2020
Bernasconi, L., Şen, S., Angerame, L., Balyegisawa, A.P., Hui, D.H.Y., Hotter, M., Hsu, C.Y., Ito, T., Jörger, F., Krassnitzer, W., Phillips, A.T., Li, R., Stockley, L., Tay, F., von Heijne Widlund, C., Wan, M., Wong, C., Yau, H., Hiemstra, T.F., Uresin, Y., Senti, G. (2020): Legal and ethical framework for global health information and biospecimen exchange – an international perspective. In: BMC Medical Ethics. https://doi.org/10.1186/s12910-020-0448-9
Magnin, A., Cabral Iversen, V., Calvo, G., Čečetková, B., Dale, O., Demlová, R., Blaskó, Gy., Keane, F., Kovacs, G.L., Levy‐Marchal, C., Monteiro, E.C., Palmisano, L., Pella, D., Portolés, A., Rascol, O., Schmid, C., Tay, F., von der Leyen, H., Ohmann, C. (2020): European survey on national harmonization in clinical research. In: Learn Health Systems, 5(2):e10220. https://doi.org/10.1002/lrh2.10220
2019
Grossmann, R., Schneider, M.A., Linecker, M., Lehn, J.-M., Nicolau, C., Traber, M., Tay, F., Vicente, D., Jetter, A., Mollet, A., Szucs, T., Graf, R., Clavien, P.-A., Limani, P. (2019): Interprofessional and interdisciplinary collaboration for early phase oncological clinical trials in academia – Myo-inositoltrispyrophosphate as model. In: Pharmacological Research, 146:104308. https://doi.org/10.1016/j.phrs.2019.04.022
Schnetzler, G., Bremgartner, M.F., Grossmann Straessle, R., Spirk, D., Tay, F., Troxler Saxer, R., Traber, M. (2019): Evolution to a Competency-Based Training Curriculum for Pharmaceutical Medicine Physicians in Switzerland. In: Frontiers in Pharmacology, 10:164. https://doi.org/10.3389/fphar.2019.00164
Magnin, A., Cabral Iversen, V., Calvo, G., Čečetková, B., Dale, O., Demlova, R., Blasko, Gy., Keane, F., Kovacs, G.L., Levy-Marchal, C., Monteiro, E.C., Palmisano, L., Pella, D., Portolés Pérez, A., Rascol, O., Schmid, C., Tay, F., von der Leyen, H., Ohmann, C. (2019): European survey on national training activities in clinical research. In: Trials, 20(1):712. https://doi.org/10.3389/fphar.2019.00164
2018
Geier, A., Eichinger, M., Stirnimann, G., Semela, D., Tay, F., Seifert, B., Tschopp, O., Bantel, H., Jahn, D., Maggio, E.M., Saleh, L., Bischoff-Ferrari, H.A., Müllhaupt, B., Dufour, J.-F. (2018): Treatment of non-alcoholic steatohepatitis patients with vitamin D: a double-blinded, randomized, placebo-controlled pilot study. In: Scandinavian Journal of Gastroenterology. https://doi.org/10.1080/00365521.2018.1501091
Signorell, C., Zimmermann, M.B., Cakmak, I., Wegmüller, R., Zeder, C., Hurrell, R., Aciksoz, S.B., Boy, E., Tay, F., Frossard, E., Moretti, D. (2018): Zinc Absorption From Agronomically Biofortified Wheat Is Similar to Post-Harvest Fortified Wheat and Is a Substantial Source of Bioavailable Zinc in Humans. In: The Journal of Nutrition. https://doi.org/10.1093/jn/nxy328