Treatment of ovarian cancer

Ovarian cancer (ovarian carcinoma) is a serious disease that requires individualized and usually multimodal therapy. The aim of treatment is to remove the tumor as completely as possible and prevent the disease from progressing, while always focusing on the patient's quality of life.

Surgery

Surgical removal of the tumor is the most important treatment step for ovarian cancer. As a rule, both ovaries, the fallopian tubes and the uterus are removed. Depending on the extent of the tumor, it may also be necessary to remove parts of the peritoneum or other affected structures. These procedures are often complex and require an experienced interdisciplinary team.

For young patients who wish to have children, we check individually whether an organ-preserving procedure is possible. We will advise you in detail on the opportunities and risks as well as possible effects on fertility.

Chemotherapy

Following the operation, chemotherapy is usually carried out to destroy any cancer cells remaining in the body. The standard treatment consists of a combination of the active substances carboplatin and paclitaxel, which are usually administered in six cycles at three-week intervals. In individual cases, chemotherapy may not be necessary for tumors at a very early stage.

We plan chemotherapy individually for each patient, depending on the stage of the tumor, general condition and concomitant diseases. Chemotherapy is usually carried out on an outpatient basis in our day clinic.

Maintenance therapy and targeted therapies

In the case of advanced ovarian cancer, so-called maintenance therapy is often recommended in addition to chemotherapy. It is continued over a longer period after successful initial therapy in order to secure the treatment success achieved and prevent a relapse (recurrence). Targeted drugs such as the monoclonal antibody bevacizumab are used here, which inhibits tumor growth and can reduce the risk of relapse. Maintenance therapy can last up to 15 months.

Further targeted therapies are available for certain genetic changes (e.g. BRCA mutation or HRD de-efficiency). We will advise you individually on the most suitable treatment options for you.

Complementary medicine for ovarian cancer

During ovarian cancer treatment at the USZ, you benefit from numerous complementary therapies. This includes, for example, complementary medical treatment, supportive sports therapies or psycho-oncological support. Our trained Cancer Care Nurses will be happy to advise you in detail.

Aftercare

After treatment is completed, regular follow-up examinations are carried out to detect a relapse at an early stage and ensure your long-term health.

These follow-up examinations include:

  • Regular check-ups
  • Imaging procedures for suspected metastases
  • Psychosocial support and advice

Responsible professionals

Isabell Witzel, Prof. Dr. med.

Director of Department, Department of Gynecology

Tel. +41 44 255 52 00
Specialties: Breast cancer treatment, Gynecological oncology, Familial breast and ovarian cancer

Eleftherios Pierre Samartzis, Dr. med.

Attending Physician, Department of Gynecology

Tel. +41 44 255 52 04
Specialties: Gynecological tumor diseases (surgical and drug therapy), Minimally invasive operations (laparoscopy, robotic surgery), Endometriosis

For patients

You can either register yourself or be referred by your primary care physician or gynecologist.
Tel. +41 44 255 50 36

Monday – Friday from 7.45 a.m. – 4.45 p.m.

Self-registration

For referrering physicians

University Hospital Zurich
Department of Gynecology
Frauenklinikstrasse 10
8091 Zurich

Tel. +41 44 255 50 36
Patient registration form

Responsible Department

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