Grants der Klinik für Thoraxchirurgie

Die Klinik für Thoraxchirurgie wird in ihrer intensiven Forschungstätigkeit von verschiedenen nationalen und internationalen Stiftungen sowie Institutionen mit einer finanziellen Zuwendung unterstützt. Folgende medizinischen Mitarbeitende erhielten für ihre Projekte einen Grant und sind namentlich im Annual Report erwähnt.

Quelle Projekttitel Projektleiter
Schweizerischer Nationalfonds EMERGE – Unraveling plEural Mesothelioma hEteRoGeneity aiming for pErsonalized treatment Schmitt-Opitz, Isabelle; Kirschner, Michaela, Meerang Mayura
Schweizerischer Nationalfonds Randomised controlled trial comparing maintenance with the addition of local ablative treatment of patients with advanced stage IV non-small cell lung cancer – salVage-Trial Schmitt-Opitz, Isabelle; Guckenberger, Matthias; Curioni-Fontecedro, Alessandra; Held, Ulrike

Quelle Projekttitel Projektleiter
ETOP European Thoracic Oncology Platform ETOP 2-11/M027911 BELIEF-phase II, open label trial with erlotinib/bevacizumab in advanced NSCLC EGFR mut+ Schmitt-Opitz, Isabelle
Johnson & Johnson AG J&J Ethicon Endo Surgery – Lungenkresoperation beim Emphysem und Mobidität der LVRS Schmitt-Opitz, Isabelle
Krebsforschung Schweiz Mesoscape 001 – pS6: construction of a multi-institutional European tissue bank (KFS-3626-02-2015 Schmitt-Opitz, Isabelle
SUVA Klinische Phase II Studie zur Evaluation intrakavitärer Chemotherapie mit Cisplatin-Fibrin nach Mesotheliom-Resektion Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung Multi-omics profiling for identification of novel circulating biomarkers for malignant pleural mesothelioma Schmitt-Opitz, Isabelle, M.Meerang, M.Kirschner
University Hospital Zurich Foundation (Iten-Kohaut Stiftung) Tracking down Non-Small Cell Lung Cancer: Targeted Sequencing of Exosomes from Primary Tumor Cell Cultures – a Proof of Principles for the TrackTHORAX Project Schmitt-Opitz, Isabelle, Raphael Werner
Baugarten Stiftung (via UZH Foundation) Surgical in comparison to bronchoscopic lung volume reduction in patients
with advanced emphysema: a multi-center randomized controlled trial
Schmitt-Opitz, Isabelle
ICON Clinical Research Limited/BMS Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab plus Etoposide/Platinum versus Etoposide/Platinum in Subjects with Newly Diagnosed Extensive-Stage Disease Small Cell Lung Schmitt-Opitz, Isabelle
Schweizerischer Nationalfonds SNF Improving Mesothelioma Patients Outcomes by Early Non-Invasive Diagnosis Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung Immune cell profiling of oligo-metastatic non-small cell lung cancer patients: Comparison of primary tumor with different sites of metastasis for impact on prognosis and immunotherapy Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung Innovation in Management of Small Pulmonary Nodules Schmitt-Opitz, Isabelle; Frauenfelder Thomas
SAKF Stiftung für angewandte Krebsforschung Establishment and long-term expansion of primary non-small cell lung
cancer organoids: setting the foundation for an individualized precision
medicine using ex-vivo cancer models
Schmitt-Opitz, Isabelle; Jungraithmayr, Wolfgang; Kirschner, Michaela; Jae Hwi, Jang; Raphael Werner
LUNGE ZÜRICH Surglcal compared to broNChoscopic lung volumE Reduction in patients with severe Emphysema: a multi-center randomized controlled trial
„SINCERE“
Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung MikroRNAs in malignen Pleuramesotheliom – Regulatoren der Therapieresistenz und mögliche Biomarker. Kirschner, Michaela
Stiftung Krebsforschung Schweiz A new therapeutic concept against lung cancer by Inhibition of CD26/DPP4 Jungraithmayr, Wolfgang
Krebsliga Zürich Targeting lung cancer by CD26/DPP4 inhibition in combination with anti-PD-L1 antibody Jungraithmayr, Wolfgang
SAKF Stiftung für angewandte Krebsforschung Targeting lung cancer by CD26/DPP4 inhibition in combination with an immune checkpoint inhibitor Jungraithmayr, Wolfgang
Swiss Lung Foundation Ein Kleintiermodell zur Rekonditionierung von marginalen Spenderlungen mit dem ex-vivo Lungenperfusions-System unter Verwendung einer neuen Perfluorkarbon-Emulsion vor Transplantation. Inci, Ilhan
Foundation A.P.Naef, Prof. hon. Ludwig K. von Segesser Extra-corporeal lung perfusion Inci, Ilhan
Jubiläumsstiftung der LLGR Inhibition of ischemia-reperfusion injury using ATP sensitive potassium channel modulators in ex vivo lung perfusion system in lung transplantation Inci, Ilhan
CytoSorbents Europe GmbH The effect of cytokine removal during ex vivo lung perfusion on post-transplant graft function Inci, Ilhan
CytoSorbents Europe GmbH Cytosorb Transplantation Inci, Ilhan
Theodor und Ida Herzog-Egli-Stiftung Effekt von NAD+ (Nicotinamidadenindinukleotid) auf den Ischämie-
Reperfusionschaden sowie die akute Organabstossung nach Lungentransplantation
Inci, Ilhan
SAKF Stiftung für angewandte Krebsforschung Stiftung für angewandte Krebsforschung: Biomarkers with enzymatic activities for improved risk stratification of lung cancer patients Hillinger, Sven
Krebsliga Zürich Sonic hedgehog signaling in malignant pleural mesothelioma Felley-Bosco, Emanuela
Schweizerischer Nationalfonds SNF RNA editing in mesothelioma: a new therapeutic target Felley-Bosco, Emanuela
Walter Bruckerhoff Stiftung The Supraspliceosome, a multi-task RNA processing machine, as novel target for diagnosis and treatement of thoracic cancers Felley-Bosco, Emanuela
SAKF Stiftung für Angewandte Krebsforschung RNA editing in mesothelioma: a new therapeutic target? Felley-Bosco, Emanuela

Quelle Projekttitel Projektleiter
ETOP European Thoracic Oncology Platform ETOP 2-11/M027911 BELIEF-phase II, open label trial with erlotinib/bevacizumab in advanced NSCLC EGFR mut+ Schmitt-Opitz, Isabelle
Johnson & Johnson AG J&J Ethicon Endo Surgery – Lungenkresoperation beim Emphysem und Mobidität der LVRS Schmitt-Opitz, Isabelle
Krebsforschung Schweiz Mesoscape 001 – pS6: construction of a multi-institutional European tissue bank (KFS-3626-02-2015 Schmitt-Opitz, Isabelle
SUVA Klinische Phase II Studie zur Evaluation intrakavitärer Chemotherapie mit Cisplatin-Fibrin nach Mesotheliom-Resektion Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung Multi-omics profiling for identification of novel circulating biomarkers for malignant pleural mesothelioma Schmitt-Opitz, Isabelle, M.Meerang, M.Kirschner
Kurt und Senta Herrmann Stiftung Tracking down Non-Small Cell Lung Cancer: Targeted Sequencing of Exosomes from Primary Tumor Cell Cultures – a Proof of Principles for the TrackTHORAX Project Schmitt-Opitz, Isabelle, Raphael Werner
University Hospital Zurich Foundation (Iten-Kohaut Stiftung) Tracking down Non-Small Cell Lung Cancer: Targeted Sequencing of Exosomes from Primary Tumor Cell Cultures – a Proof of Principles for the TrackTHORAX Project Schmitt-Opitz, Isabelle, Raphael Werner
Baugarten Stiftung (via UZH Foundation) Surgical in comparison to bronchoscopic lung volume reduction in patients
with advanced emphysema: a multi-center randomized controlled trial
Schmitt-Opitz, Isabelle
ICON Clinical Research Limited/BMS Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab plus Etoposide/Platinum versus Etoposide/Platinum in Subjects with Newly Diagnosed Extensive-Stage Disease Small Cell Lung Schmitt-Opitz, Isabelle
Schweizerischer Nationalfonds SNF Improving Mesothelioma Patients Outcomes by Early Non-Invasive Diagnosis Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung Immune cell profiling of oligo-metastatic non-small cell lung cancer patients: Comparison of primary tumor with different sites of metastasis for impact on prognosis and immunotherapy Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung Innovation in Management of Small Pulmonary Nodules Schmitt-Opitz, Isabelle; Frauenfelder Thomas
LUNGE ZÜRICH Surglcal compared to broNChoscopic lung volumE Reduction in patients with severe Emphysema: a multi-center randomized controlled trial
„SINCERE“
Schmitt-Opitz, Isabelle
SAKF Stiftung für angewandte Krebsforschung The role of microRNAs in malignant pleural mesothelioma progression and therapy resistance Kirschner, Michaela
SAKF Stiftung für angewandte Krebsforschung MikroRNAs in malignen Pleuramesotheliom – Regulatoren der Therapieresistenz und mögliche Biomarker. Kirschner, Michaela
Stiftung Krebsforschung Schweiz A new therapeutic concept against lung cancer by Inhibition of CD26/DPP4 Jungraithmayr, Wolfgang
Krebsliga Zürich Targeting lung cancer by CD26/DPP4 inhibition in combination with anti-PD-L1 antibody Jungraithmayr, Wolfgang
SAKF Stiftung für angewandte Krebsforschung Targeting lung cancer by CD26/DPP4 inhibition in combination with an immune checkpoint inhibitor Jungraithmayr, Wolfgang
Swiss Lung Foundation Ein Kleintiermodell zur Rekonditionierung von marginalen Spenderlungen mit dem ex-vivo Lungenperfusions-System unter Verwendung einer neuen Perfluorkarbon-Emulsion vor Transplantation. Inci, Ilhan
Foundation A.P.Naef, Prof. hon. Ludwig K. von Segesser Extra-corporeal lung perfusion Inci, Ilhan
Jubiläumsstiftung der LLGR Inhibition of ischemia-reperfusion injury using ATP sensitive potassium channel modulators in ex vivo lung perfusion system in lung transplantation Inci, Ilhan
Schweizerischer Nationalfonds SNF Reconditioning of marginal donor lung in ex vivo lung perfusion system using perfluorocarbon based oxygen carrier. Inci, Ilhan
CytoSorbents Europe GmbH The effect of cytokine removal during ex vivo lung perfusion on post-transplant graft function Inci, Ilhan
Swiss Lung Foundation Bau einer Unterdruckkammer für zu transplantierende Lungen Inci, Ilhan
Theodor und Ida Herzog-Egli-Stiftung Effekt von NAD+ (Nicotinamidadenindinukleotid) auf den Ischämie-
Reperfusionschaden sowie die akute Organabstossung nach Lungentransplantation
Inci, Ilhan
SAKF Stiftung für angewandte Krebsforschung Stiftung für angewandte Krebsforschung: Biomarkers with enzymatic activities for improved risk stratification of lung cancer patients Hillinger, Sven
SAKF Stiftung für angewandte Krebsforschung Innovative Abklärungsmöglichkeiten des kleinen pulmonalen Rundherdes Hillinger, Sven
Krebsliga Zürich Sonic hedgehog signaling in malignant pleural mesothelioma Felley-Bosco, Emanuela
Schweizerischer Nationalfonds SNF RNA editing in mesothelioma: a new therapeutic target Felley-Bosco, Emanuela
Walter Bruckerhoff Stiftung The Supraspliceosome, a multi-task RNA processing machine, as novel target for diagnosis and treatement of thoracic cancers Felley-Bosco, Emanuela
SAKF Stiftung für Angewandte Krebsforschung RNA editing in mesothelioma: a new therapeutic target? Felley-Bosco, Emanuela

Quelle

​Projekttitel

​Projektleiter

Walter Bruckerhoff Stiftung
The Supraspliceosome, a multi-task RNA processing machine, as novel target for diagnosis and treatment of thoracic cancer
Emanuela Felley-Bosco
Stiftung für Angewandte Krebsforschung
RNA editing in mesothelioma: a new therapeutic target
Emanuela Felley-Bosco
Schweizer Nationalfond
​Improving Mesothelioma Patients Outcomes by Early Non-Invasive Diagnosis
​I. Opitz
​Iten-Kohaut Stiftung
Tracking down Non-Small Cell Lung Cancer: on the road to personalized medicine for Lung Cancer (TrackTHORAX)​
I. Opitz​
​Stiftung für Angewandte Krebsforschung
Multi-omics profiling for identification of novel circulating biomarkers for malignant pleural mesothelioma​
I. Opitz, M. Meerang, M. Kirschner​​
​Stiftung für Angewandte Krebsforschung
Proteogenomic biomarker analysis of malignant pleural mesothelioma​
P. Wild, I. Opitz​​
​Polianthes Stiftung
Next Generation Sequencing of Malignant Pleural Mesothelioma for Therapy Response Prediction​
P. Wild, I. Opitz​​
​Krebsliga Schweiz
​Mesoscape 001-pS6: Construction of a multi-institutional European Tissuebank
​I. Opitz
​Kurt und Senta Hermann Stiftung
​Tracking down NSCLC: targeted sequencing of exosomes from primary tumor cell cultures – a proof of principle for the TrackTHORAX Project
​R. Werner, I. Opitz
​Stiftung für Angewandte Krebsforschung
​The role of microRNAs in malignant pleural mesothelioma progression and therapy resistance
​M. Kirschner, I. Opitz
​Kantonalzürcherische Krebskommission
​The role of microRNAs in malignant pleural mesothelioma progression and resistance to chemo- and immunotherapy
​M. Kirschner

​Krebsliga Zürich

​Targeting Lung Cancer by CD26/DPP4-inhibition in combination with anti-PD-L1 antibody
​W. Jungraithmayr

Quelle Projekttitel Projektleiter
Schweizer Nationalfond
​Malignant Pleural Mesothelioma – an integrative approach for better outcomeImproving Mesothelioma Patients Outcomes by Early Non-Invasive Diagnosis
​I. Opitz
​Stiftung für Angewandte Krebsforschung
Multi-omics profiling for identification of novel circulating biomarkers for malignant pleural mesothelioma​
I. Opitz, M. Meerang, M. Kirschner​​

Quelle

Projekttitel

Projektleiter

Schweizer Nationalfond
​Malignant Pleural Mesothelioma – an integrative approach for better outcome
​I. Opitz
​Stiftung für Angewandte Krebsforschung
​Multi-omics profiling for identification of novel circulating biomarkers for malignant pleural mesothelioma
I. Opitz, M. Meerang, M. Kirschner​
​Stiftung für Angewandte Krebsforschung
Proteogenomic biomarker analysis of malignant pleural mesothelioma​​
P. Wild, I. Opitz​
​Polianthes Stiftung
Next Generation Sequencing of Malignant Pleural Mesothelioma for Therapy Response Prediction ​
P. Wild, I. Opitz​
​Verein Lunge Zürich
MicroRNAs as prognostic and predictive tumour markers assisting the selection of patients with malignant pleural mesothelioma for multimodality treatment​
​I. Opitz, M. Kirschner
​Krebsliga Schweiz
Mesoscape 001-pS6: Construction of a multi-institutional European Tissuebank ​
I. Opitz​
​Stiftung für Angewandte Krebsforschung
Proteogenomic biomarker analysis of malignant pleural mesothelioma​
I. Opitz, M. Meerang, M. Kirschner​
​Swiss National Science Foundation Sinergia grant
From asbestos exposure to cancer: a systemic approach to detect loss of homeostatic control in the mesothelial environment​
​E. Felley-Bosco
​Walter Bruckerhoff Stiftung
​Targeting epigenetic deregulation
​E. Felley-Bosco
Polianthes Stiftung
​Mechanisms underlying development of resistance and progression to mesenchymal phenotype in mesothelioma
E. Felley-Bosco​
Schweizer Nationalfond
Reconditioning of marginal donor lung in ex vivo lung perfusion system using perfluorocarbon based oxygen carrier
I. Inci​
​A. P. Naef Stiftung
Inhibition of ischemia reperfusion injury using ATP sensitive potassium channel modulators in ex vivo lung perfusion system in lung transplantation ​
​I. Inci

​Zürcher Lungenstiftung

A small animal model for reconditioning marginal donor lung in ex vivo lung perfusion system using an advanced perfluorocarbon emulsion before transplantation   ​
​I. Inci
​Lungenliga Graubünden
​Inhibition of ischemia-reperfusion injury using ATP sensitive potassium
channel modulators in ex vivo lung perfusion system in lung transplantation
I. Inci​
​Sophien Stiftung
​A new therapeutic concet against lung cancer by inhibition of CD26/DPP4
​W. Jungraithmayr
„​Clinical Scientist“, Medizinische Hochschule Brandenburg.
​Targeting lung cancer by CD26-inhibition
​W. Jungraithmayr

Quelle

Projekttitel

Projektleiter

​Zürcher Krebsliga
​Prognostic Marker for MPM
​I. Opitz
​SNF Overhead
​​I. Opitz
​Stiftung Becon
​Gewebe- und Datenbank für das MPM – ein paneuropäisches Projekt
​I. Opitz
​Vontobel Stiftung
​MikroRNAs als prognostische und prädiktive Tumormarker für die multimodale  Behandlung des malignen Pleuramesothelioms
​I. Opitz
​Lunge Zürich
​MicroRNAs as prognostic and predictive tumour markers assisting the selection of patients with malignant pleural mesothelioma for multimodality treatment
​I. Opitz
​SNF Professorship
​MPM – an integral approach for better outcome
​I. Opitz
​Krebsforschung Schweiz
​Mesoscape 001-pS6: Construction of a multi-institutional European Tissuebank
​I. Opitz
​Polianthes Foundation
Comprehensive Investigation of Predictive Biomarkers for Chemotherapy ​Response and Novel Drug Targets in Patients with MPM by Next Generation Sequencing
​I. Opitz
Stiftung für Angewandte Krebsforschung
​Multi-omics profiling for identification of novel circulating biomarkers for malignant pleural mesothelioma
​I. Opitz
Swiss National Science​Foundation Sinergia grant
​From asbestos exposure to cancer: a systemic approach to detect loss of homeostatic control in the mesothelial environment
​E. Felley-Bosco
​Walter Bruckerhoff Stiftung
​Targeting epigenetic deregulation
​E. Felley-Bosco
​​Polianthes Foundation
Mechanisms underlying development of resistance and progression to mesenchymal phenotype in mesothelioma
​E. Felley-Bosco
​Innovationspool
Implementierung der „Synapse 3D®“ Software von Fujifilm zur Planung und​Simulation von (minimal-invasiven) anatomischen Lungenresektionen, Lungenvolumenreduktionschirurgie und minimal-invasiven Zugängen
​C. Caviezel
​Hartmann Müller Stiftung
​The role of cytokine filtration during ex vivo lung perfusion
​I. Inci
​Hermann Klaus Stiftung
​Ex vivo reconditioning of donor lungs with Trimetazidine after prolonged cold ischemia
​I. Inci
​Lungen Liga Zurich
​The effect of lung volume reduction surgery on outcome after lung transplantation in patients with emphysema
​I. Inci
​Innovationspool
​Assessment and reconditioning of donor lungs with ex vivo lung perfusion system
​I. Inci
​Schweizerischer Nationalfonds
​Suppression of lung tumor growth by CD26 /DPP4-inhibition
​W. Jungraithmayr
​Helene Bieber Fonds
​The CD26-costimutatory pathway is critical for Th17-mediated lung transplant improvement
​W. Jungraithmayr
​Hartmann-Müller Stiftung
​The protective effect of local anesthetics on primary graft dysfunction after experimental lung transplantation
​W. Jungraithmayr
​Kurt und Senta Herrmann- Stiftung
​Blockade of CD26/DPP4 – co-stimulation to improve lung transplant survival
​W. Jungraithmayr
​Stiftung für wissenschaftliche
Forschung
​Ein neues Therapiekonzept zur Bekämpfung des Lungenkarzinoms durch
Hemmung der CD26/DPP4
​W. Jungraithmayr

​Forschungskredit, University Zurich

​The protective role of CD26/DPP4-inhibition in lung transplantation – a preclinical study
​W. Jungraithmayr
​Assistant Professorship,
University Zurich
​Lungentransplantation
W. ​Jungraithmayr
​Development program
“Filling the Gap”
​The protective role of CD26/DPP4-inhibition in lung transplantation – a preclinical study
​W. Jungraithmayr
​Hermann Klaus-Stiftung,
University Zurich
​A new therapeutic concept against lung cancer through inhibition of CD26/ DPP4
​W. Jungraithmayr
​Stiftung für Krebsbekämpfung, University Zurich
​Ein neues Therapiekonzept zur Bekämpfung des Lungenkarzinoms durch  Hemmung der CD26/DPP4
​W. Jungraithmayr
​Stiftung für Angewandte Krebsforschung
​Biomarkers with enzymatic activities for improved risk stratification of lung cancer patients
​S. Hillinger

Quelle

Projekttitel

Projektleiter

Swiss National Science Foundation

​From asbestos-exposure to cancer: a systemic approach to detect loss of homeostatic control in the mesothelial environment

​E. Felley-Bosco

​Baumgarten Stiftung

Preclinical Malignant Pleural Mesothelioma models to accelerate clinical research on targeted therapy

​E. Felley-Bosco

Walter Bruckerhoff Stiftung

​Targeting epigenetic deregulation

​E. Felley-Bosco

Polianthes Foundation

​Overcoming development of resistance and progression to mesenchymal phenotype in mesothelioma

​E. Felley-Bosco

Polianthes Foundation

​Comprehensive investigation of predictive biomarkers for chemotherapy response and novel drug targets in patients with MPM by next generation sequencing

I. Schmitt-Opitz

Krebsforschung Schweiz

​Mesoscape 001-pS6: Construction of a multi-institutional European tissue bank

​I. Schmitt-Opitz

Swiss National Science Foundation

​Magnetic resonance imaging for the detection of chronic lung allograft rejection in mouse lung transplantation

W. Jungraithmayr (Co-Applicant)
Applicant: PD Dr. A. Boss

​Swiss National Science Foundation, Förderungsprofessuren

Malignant Pleural Mesothelioma – an integral approach for better outcome

​I. Schmitt-Opitz

Forschungskredit der Universität Zürich

​Attenuation of acute lung allograft rejection by CD26 inhibition – a preclinical model

​W. Jungraithmayr

​Stiftung für wissenschaftliche Forschung, Zürich

​Lung tumor growth reduction by CD26 inhibition

​W. Jungraithmayr

​Assistenz-Professur an der UZH

​Lungentransplantation

​W. Jungraithmayr

Förderungsprogramm „Filling the Gap“, FTG-1617-02

Attenuation of acute lung allograft rejection by CD26 inhibition – a preclinical model

​W. Jungraithmayr

​Hermann Klaus-Stiftung

​Primary lung tumor growth inhibition by CD26

​W. Jungraithmayr

Innovationspool

Assessment and reconditioning of donor lungs with ex vivo lung perfusion system

I. Inci

​Lungenliga Zürich

​Ex vivo reconditioning of donor lungs with inhaled N-Acetyl cysteine after prolonged cold ischemia

​I. Inci

Hermann-Klaus Stiftung​

​Ex vivo reconditioning of donor lungs with Trimetazidine after prolonged cold ischemia

​I. Inci

​Hermann-Klaus Stiftung​

​Ex vivo reconditioning of donor lungs with inhaled N-Acetyl cysteine after prolonged cold ischemia

I. Inci​

Hartmann-Müller Stiftung, Zürich​

​The role of cytokine filtration during ex vivo lung perfusion

​I. Inci

Lunge Zürich

​​MicroRNAs as prognostic and predictive tumor markers assisting the selection of patients with Malignant Pleural Mesothelioma for multimoda-lity treat-ment

​​I. Schmitt-Opitz, M. Kirschner

​Dr. Arnold U. u. Susanne Huggenberger-Bischoff Stiftung zur Krebsforschung

(Krebsstiftung)

In vivo study of the efficacy of a dual phosphatidylinositol-3-kinase (PI3K)-/mTOR-inhibitor in the treatment of malignant pleural mesothelioma​

​W. Weder, I. Schmitt-Opitz

​Krebsliga Zürich

​Prognostic Marker for Malignant Pleural Mesothelioma

I. Schmitt-Opitz

BECON AG Foundation

​Prognostische Marker für das Maligne Pleuramesotheliom

​I. Schmitt-Opitz

Vontobel Stiftung

​MikroRNAs als prognostische und prädikative Tumormarker für die multimodale Behand-lung des malignen Pleura-mesothelioms

​I. Schmitt-Opitz, M. Kirschner

​Stiftung für angewandte Krebsforschung

​Activity based protein profiling in human lung cancer biopsies

​W. Weder, S. Hillinger, S. Arni

Novartis Pharma AG Basel

 

​Identification and validation of drug targets and biomarkers for COPD/emphysema and other end-stage lung disease

​W. Weder, S. Hillinger

EMDO-Stiftung, Switzerland

Impact of sevoflurane anesthesia on primary graft dysfunction after experimental mouse lung transplantation

​W. Jungraithmayr

​Universität Zürich, Projektförderung (Abt.I-III)

​Suppression of lung tumor growth by CD26/DPP4-inhibition

W. Jungraithmayr​

​Kurt und Senta Herrmann-Stiftung, Liechtenstein, Vaduz

​Blockade of CD26/DPP4-costimulation to improve lung transplant

survival

​W. Jungraithmayr

Helene Bieber-Fonds

The CD26-costimlatory pathway is critical for Th17-mediated lung transplant improvement

W. Jungraithmayr

Quelle

Projekttitel

Projektleiter

​Matching Fund UZH 2012
​Preclinical investigation of the role of hedgehog signaling on mesothelioma recurrence
​I.Schmitt-Opitz
​Matching Fund UZH 2011
​Prognostic Marker for Malignant Pleural Mesothelioma
​I.Schmitt-Opitz
​Krebsliga Zürich
​Prognistic Marker for Malignant Pleural Mesothelioma
​I.Schmitt-Opitz
​BECON AG Foundation
​Prognostische Marker für das maligne Pleuramesotheliom
​I.Schmitt-Opitz
​Vontobel Stiftung
​MikroRNAs als prognostische und pädikative Tumormarker für die multimodale Behandlung des malignen Pleuramesothelioms
​I.Schmitt-Opitz
​Krebsliga Zürich
​Activity based protein profiling in human lung cancer biopsies
​W.Weder,S.Hillinger, S.Arni
​Novartis Pharma AG, Basel
Identification and validation of drug targets and biomarkers for COPD/emphysema and other end-stage lung disease​
​W.Weder, S.Hillinger
​Matching Fund UZH 2012
​Improvement of ischemia-reperfusion injury in murine lung transplatns by regenerative stern cells via inhibition of CD26/DPPIV
​W.Jungraithmayr
​EMDO-Stiftung 2013, Zurich
​Impact of sevoflurane anesthesia on primary graft dysfunction after experimental mouse lung transplantation
​W.Jungraithmayr
​Universität Zürich, Projektförderung (Abt.I-III)
​​Suppression of lung tumor growth by CD26/DPP4-Inhibition
​W.Jungraithmayr
​Hermann-Klaus Stiftung, Zürich
​Ex vivo reconditioning of donor lungs with Trimetazidine after prolonged cold ischemia
​I.Inci

​Hartmann-Müller Stiftung, Zürich

​Ex vivo reconditioning of donor lungs with inhaled N-Aceteyl cysteine after prolonged cold ischemia
​I.Inci

Quelle ​Projektitel ​Projektleiter
Swiss National Science Foundation
Immunotherapy for lung cancer
S. Hillinger
Swiss National Science Foundation
The role of CD26/DPP IV and SDF-1 in pulmonary ischemic injury in a mouse
W. Jungraithmayr
Swiss National Science Foundation
Micro Computer-Tomographie für in-vivo Bildgebung
W. Jungraithmayr
(Co-Applicant)
Applicant: PD Dr. A. Boss
Hartmann-Müller Stiftung Zürich – 2012
Improvement of ischemia-reperfusion injury in muring lung transplants by stem cells via inhibition of DPP4 (Ges-Nr: 1591)
W. Jungraithmayr
Lungenliga Zürich
Rekonditionierung durch Magensäure geschädigter Lungentransplantate
Nicht-Herz-schlagenden Spendern
I. Inci
​Innovationspool
​Assessment and recondi-tioning of donor lungs with ex vivo lung perfusion system
​I.Inci
​Lungenliga, Zürich
​Ex vivo reconditioning of donor lungs with inhaled N-Acetyl cysteine after prolonged cold ischemia
​I.Inci
​Swiss National Science Foundation
​In-Vivo Bioreactor for the reepithelialization of tissue engineered trachea
W.Weder​
Dr. Arnold U. u. Susanne Huggenberger-Bischoff Stiftung zur Krebsforschung
(Krebsstiftung)
In vivo study of the efficacy of a dual phosphatidylino-sitol-3-kinase (PI3K)-/mTOR-inhibitor in the treatment of malignant pleural mesothelioma
W. Weder, I. Schmitt-Opitz
​BECON AG Foundation
​Prognostische Marker für das Maligne Pleuramesotheliom
​W. Weder, I. Schmitt-Opitz
Matching Fund UZH 2011
Malignant Pleural Mesothelioma – an integral approach for better outcome
I. Schmitt-Opitz
Matching Fund UZH 2012
Preclinical investigation of the role of hedgehog signaling on
mesothelioma recurrence
I. Schmitt-Opitz
Matching Fund UZH 2011
Prognostic Marker for Malig-nant Pleural Mesothelioma
I. Schmitt-Opitz
Krebsliga Zürich
Prognostic Marker for Malig-nant Pleural Mesothelioma
I. Schmitt-Opitz
​Swiss National Science Foundation
Förderungsprofessuren
​Malignant Pleural Mesothelioma – an integral approach for better outcome
​I. Schmitt-Opitz
Krebsliga Zürich
Activity based protein profiling in human lung cancer biopsies
W. Weder, S. Hillinger,
S. Arni
Novartis Pharma AG Basel
Identification and validation of drug targets and biomarkers for COPD/ emphysema and other end-stage lung disease
W. Weder, S. Hillinger
Matching Fund UZH 2012
Improvement of ischemia-reperfusion injury in murine lung transplants by regenerative stem cells via inhibition of CD26/DPPIV
W. Jungraithmayr
Matching Fund UZH 2011
Tolerance induction via NK cell mediated elimination of donor antigen presenting cells in mouse lung transplants
W. Jungraithmayr
EMDO-Stiftung 2013, Zurich, Switzerland
Impact of sevoflurane anesthesia on primary graft dysfunction after experimental mouse lung transplantation
W. Jungraithmayr

Quelle

Projekttitel

Projektleiter

Hartmann-Müller Stiftung Zürich – 2012
Improvement of ischemia-reperfusion injury in muring lungtransplants by stem cells via inhibition of DPP4 (Ges-nr: 1591)
W. Jungraithmayr
Swiss National Science Foundation
Förderungsprofessuren
Malignant Pleural Mesothelioma – an integral approach for
better outcome
I. Schmitt-Opitz
Swiss National Science Foundation
The role of CD26/DPP IV and SDF-1 in pulmonary ischemic
injury in a mouse
W. Jungraithmayr
Swiss National Science Foundation
Immune targeted therapy for lung cancer
S. Hillinger
Swiss National Science Foundation
In-Vivo Bioreactor for the reepithelialization of tissue engineered
trachea
W. Weder
Swiss National Science Foundation
Micro Computer-Tomographie für in-vivo Bildgebung
W. Jungraithmayr (Co-
Applicant) Applicant: PD
Dr. A. Boss
Swiss National Science Foundation
Magnetic resonance imaging for the detection of chronic lung allograft rejection in mouse lung transplantation
W. Jungraithmayr (Co-
Applicant) Applicant: PD
Dr. A. Boss
Lungenliga Zürich
Rekonditionierung durch Magensäure geschädigter Lungentransplantate
Nicht-Herz-schlagenden Spendern
I. Inci
Dr. Arnold U. u. Susanne Huggenberger-
Bischoff Stiftung zur Krebsforschung
(Krebsstiftung) Co-applicant
In vivo study of the efficacy of a dual phosphatidy-linositol-3-kinase (PI3K)-/mTOR-inhibitor in the treatment of malignant pleural mesothelioma
W. Weder, I. Schmitt-
Opitz

Quelle

Projekttitel

Projektleiter

Swiss National Science Foundation
Immune targeted therapy for lung cancer
S. Hillinger
Swiss National Science Foundation
NF In-Vivo Bioreactor for the reepithelialization of tissue engineered trachea
W.Weder
Swiss National Science Foundation
The role of CD26/DPP IV and SDF-1 in pulmonary ischemic injury in a mouse lung transplantation model
W. Jungraithmayr
Swiss National Science Foundation
Föderungsprofessur Isabelle Schmitt-Opitz
I. Schmitt-Opitz
Covidien Inc
Covidien LUN-06-002
W. Weder
Krebsliga Zürich
Adjuvante intrapleurale Spüllösung nach Pleuropneumonektomie nach malignen Pleuramesotheliom
I. Schmitt-Opitz
F. Hoffmann-La Roche Ltd., Bern
ETOP Lungscape Database collaboration between ETOP and Chinese
investigators
W. Weder
Lungen Liga
Lungenliga Ex vivo evaluation and resuscitation of human donor lungs rejected for transplantation
W. Weder
ETOP European Thoracic Oncology Platform
ETOP Lungscape
W. Weder
Krebsliga Zürich
Activity based protein profiling in human lung cancer biopsies
W. Weder

Quelle ​Projekttitel Projektleiter
Swiss National Science Foundation
Immune targeted therapy for lung cancer
S. Hillinger
Swiss National Science Foundation
Trachea reconstruction using novel tissue
engineered constructs
W. Weder
Swiss National Science Foundation
The role of CD26/DPP IV and SDF-1 in pulmonary
ischemic injury in a mouse lung transplantation model
W. Jungraithmayr
Krebsliga Zürich
Prognostic markers for malignant pleural mesothelioma
I. Schmitt-Opitz
Krebsliga Zürich
Establishment of an integrated tumor tissue platform
and its application for comprehensive analyses of
molecular parameters in lung tumors
W. Weder
Krebsliga Zürich
Adjuvante intrapleurale Spüllösung nach Pleuropneumo-
nektomie beim malignen Pleuramesotheliom

I. Schmitt-Opitz

Fellowship European Society of Medical Oncology
Intrapleural therapy after surgery for malignant pleural
mesothelioma
I. Schmitt-Opitz
Lungen Liga
Attenuation of ischemia-reperfusion injury by N-Acetylcysteine
after lung transplantation
I.Inci
Lungen Liga
Reconditioning of category 3 non-heart beating donor
lungs insulted to gastric aspiration: Utilization of ex vivo
lung perfusion system
I.Inci
Dr. U. Arnold and Susanne Huggenberger-Bischoff Stiftung
zur Krebsforschung
„Activity based protein profiling in human lung cancer biopsies
S. Arni
Krebsliga Zürich
Preclinical pharmacocinetic study for evaluation oif intrapleural
treatment with Cisplatin-fibrin after pneumonectomy for malig-
nant pleural mesothelioma
I. Schmitt-Opitz
Becon AG
Prognostische Marker für das maligne Pleura-mesothelioma
I. Schmitt-Opitz, W. Weder
Matching Fund
Prognostic Marker for Malignant Pleural Meso-thelioma
I. Schmitt-Opitz
Matching Fund
Activity based protein profiling in human lung cancer biopsies
W. Weder
Krebsliga Zürich
Activity based protein profiling in human lung cance biopsies
S. Arni