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CRPS and 3D-Skin model

Complex regional pain syndrome (CRPS)

Complex regional pain syndrome (CRPS) is a condition of extreme pain affecting a part of the body with clinical features including chronic inflammation, sensory and motor dysfunctions and changes to skin and bones. Symptoms usually appear after trauma or surgery.

3D skin model

Current in vitro models for skin diseases are based on cell monolayers, not considering the complex interaction within the 3-dimensional architecture of organs and the interactions of cells and the environment. Consequently, we observe a rather poor predictable power of pre-clinical cell-based drug screening assays.

Group Members

Florian Brunner, Prof. Dr. med.

Chief of Rheumatology, Balgrist

Tel. Tel. +41 44 386 35 01