Postdoktorandin Klinik für Neonatologie
Tumor oxygenation is one of the important biomarkers for diagnosis of cancer. Tumor hypoxia is often heterogeneous, i.e. showing different oxygenation levels in different parts of a single tumor. However, the lack of non-invasive measurement of distribution of tissue oxygenations sets obstacles to achieve this valuable information successfully.
Near Infrared Optical Tomography (NIROT) shows great potential to image tumor oxygenation levels non-invasively. NIROT is intrinsically sensitive to the quantities of Oxy-haemoglobin (O2Hb) and deoxy-haemoglobin (HHb), two major molecules to determine tissue oxygenation. Moreover, the use of non-ionizing region of light and harmless intensities gives NIROT the strength to image objects non-invasively and continuously. My project aims to develop a NIROT system for clinical applications.