CCCZ Fellows Symposium

The CCCZ Fellows Program supports outstanding post-doctoral fellows and clinician-scientists to carry out translational research projects in laboratories and clinical departments of the Comprehensive Cancer Center Zurich. The program supports 18 innovative cancer research projects, 18 talented fellows, 36 principal investigators from 19 CCCZ clinical and research departments. The program is supported by the University and Medical Faculty of Zurich (CHF 4.9 Mio., 2018-2022). The 2021 CCCZ Fellows Symposium showcases the research projects of CCCZ fellows of the first and second funding period of the program.


University of Zurich
Aula KOL-G-201
Rämistrasse 71
8006 Zürich




14.30 - 19.45 Uhr



14.30 Uhr Welcome
Prof. Dr. med. Markus Manz / Prof. Dr. med. Matthias Guckenberger
Session I – Chairs: Prof. Dr. Anne Müller and Prof. Dr. Maries van den Broek
14.45 Uhr Inhibitors of Bcl-2 and Bruton’s tyrosine kinase synergize to abrogate diffuse large B-cell lymphoma growth in vitro and in orthotopic xenotransplantation models
Dr. Katrin Bertram / Prof. Dr. Anne Müller / Prof. Dr. med Thorsten Zenz
15.00 Uhr Alternative combined radioimmunotherapy to overcome treatment-related resistances
Dr. Carmen Yong / Prof. Dr. Martin Pruschy / Prof. Dr. med Onur Boyman
15.15 Uhr Deciphering tumorigenesis driven by replication-associated DNA damage
Dr. Nina Desboeufs / Prof. Dr. Massimo Lopes / Prof. Dr. med. Achim Weber
15.30 Uhr Validation of mono-ADP-ribosylated proteins as diagnostic and prognostic tool in oncology
PD Dr. Peter Schraml / Prof. Dr. Michael O. Hottiger
15.45 Uhr Tertiary lymphoid structures in metastatic melanoma and non-small cell lung cancer tissues as predictive markers for the outcome of checkpoint inhibitor treatment
Dr. med. Oltin T. Pop / Prof. Dr. Maries van den Broek / Prof. Dr. med. Lukas Flatz
16.00 Uhr Break
Session II – Chairs: Prof. Dr. Bernd Bodenmiller and Prof. Dr. med. Holger Moch
16.30 Uhr Immuno-radiomics as a novel prognostic and predictive biomarker in malignant melanoma treated with immune checkpoint inhibition –a multi-systems approach
Dr. Simon Burgermeister / Prof. Dr. Mitchell Levesque / Prof. Dr. med. Matthias Guckenberger
16.45 Uhr Investigating the functional role of cellular phenotypes in melanoma targeted therapy
Dr. Jelena Vasilevska / Prof. Dr. Lukas Sommer / Prof. Dr. med. Reinhard Dummer
17.00 Uhr Investigating reactivation of embryonic programs in inflammation and metastatic cancer of the colon
Dr. Hassan Fazilaty / Prof. Dr. Konrad Basler / Prof. Dr. med. Dr. phil. Gerhard Rogler
17.15 Uhr Targeting the transcriptional network architecture driven by the oncogenic TCF3-HLF fusion
Dr. Valdemar Priebe / Prof. Dr. Raffaella Santoro / Prof. Dr. med. Dr. sc. nat. Jean-Pierre Bourquin
17.30 Uhr Ida de Pottère-Leupold and Dr. Iur. Erik de Pottère Cancer Research Award for doctoral students – Johanna Wagner, PhD
17.40 Uhr Ida de Pottère-Leupold and Dr. Iur. Erik de Pottère Cancer Research Award for clinician-scientists – Tobias Weiss, MD/PhD
17.50 Uhr Ida de Pottère-Leupold and Dr. Iur. Erik de Pottère Cancer Research Award –Ceremony
Prof. Dr. med. Markus Manz / Prof. Dr. med. Matthias Guckenberger
18.00 Uhr Break
Session III – Chairs: Prof. Dr. Konrad Basler and Prof. Dr. Raffaella Santoro
18.15 Uhr An integrative approach to characterize and exploit the epigenetic landscape in glioblastoma
Dr. Martin Cusack / Prof. Dr. Tuncay Baubec / Prof. Dr. med. Michael Weller
18.30 Uhr Butyrate-producing bacteria ameliorate CRC tumorigenesis through modulation of immune responses
Dr. Ana Montalban-Arques / Prof. Dr. Lubor Borsig / Prof. Dr. med. Michael Scharl
18.45 Uhr Ageing-derived IL-1 promotes Tet2+/-clonal expansion in mouse models of clonal hematopoiesis
Dr. Francisco Caiado / Prof. Dr. Jacob Corn / Prof. Dr. med. Markus G. Manz
19.00 Uhr The immune environment of acute myeloid leukemia
Dr. Stefanie Kreutmair / Prof. Dr. Burkhard Becher / PD Dr. med. Alexandre Theocharides
19.15 Uhr Apéro


Prof. Dr. Matthias Guckenberger, Director Outreach and Education
Silke Uflacker, Outreach and Event Manager
Comprehensive Cancer Center Zurich


Only for employees of University Hospital Zurich (USZ), University of Zurich (UZH), University Children’s Hospital Zurich and Balgrist University Hospital

Important: Admission according to the 3G rule. Participants must show a valid COVID certificate in addition to the existing measures.

Verantwortlicher Fachbereich