Hypothalamic astrocytes play pivotal roles in both nutrient availability sensing and the modulation of synaptic plasticity. Although neurons rely greatly on glucose-derived fuels, astrocytes have high capacity for fatty acid oxidation in mitochondria. We showed that genetic manipulations of fatty acid levels determines the susceptibility to diet-induced obesity.
Center Director, NGN Research Center, Klinik für Neonatologie
Attending neonatologist, Klinik für Neonatologie
Developmental pediatrician, Klinik für Neonatologie