Hypothalamic astrocytes play pivotal roles in both nutrient availability sensing and the modulation of synaptic plasticity. Although neurons rely greatly on glucose-derived fuels, astrocytes have high capacity for fatty acid oxidation in mitochondria. We showed that genetic manipulations of fatty acid levels determines the susceptibility to diet-induced obesity.
Online
21.10.2021
15.00-16.00 (GMT+2:00)